In the face of all these difficulties, it is reasonable to ask why anyone bothers with such studies. But they do, in the interests of establishing scientifically valid forms of diagnosis and treatment. Attempts to do this in relation to food intolerance are many and varied, and we will not try to cover them all. What matters in such studies is the care with which they are designed and the details of how they are carried out. To assess a trial properly, one must look carefully at the details and we will therefore concentrate on five trials – two dealing with rheumatoid arthritis, two dealing with irritable bowel syndrome, and one dealing with migraine. These trials are the main ones carried out in Britain within the last eight years, and they are among the most scientific attempts to evaluate the food-intolerance concept.
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