It can be taken every eight hours (three times a day) and, because this is easier, more people are likely to take it properly. Ampicillin is marketed as Penbritin and Austrapen, and amoxycillin as Mox-acin and Amoxil.

The tetracyclines are a group of bacteriostatic antibiotics produced from a number of moulds. They have a wide range of activity against many organisms which are insensitive to penicillin.

These drugs are also active against some of the larger viruses and related organisms which fall between bacteria and viruses in their characteristics.

Bacteria are organisms with a cell wall containing the active ingredients of the cell. They are capable of independent reproduction.

Viruses are smaller particles without a cell wall and consisting mainly of RNA or DNA, proteins which make up the nucleus of cells and which contain the genetic material.

Viruses can reproduce only inside cells of the host but bacteria can be grown in the test tube, if suitable nutrient is available. A virus can grow only in a suitable cell culture, where it reproduces itself inside a living cell.

*201/71/1*

May 8

Could you be born with cells that have within them the possibility of growing into a full-blown case of endometriosis? In answering this question, researchers noted that many women do not have any classical symptoms of endometriosis while having the disease. Another dilemma involved women who had undergone abdominal surgery; there it was found that masses had developed that contained endometriosis like cells. That is, these patients appeared to have the disease, but in fact, they did not. How might this happen?

Noteworthy embryo logical studies uncovered some fascinating evidence. During intrauterine life, the fetal reproductive organs germinate from different types of cells. Vaginal tissue originates from a different set of genetic blueprints than uterine tissue, although both organs have the quality and capability of, for example, elasticity to accommodate childbearing. These embryonic studies went on to show that the tissue lining the ovaries, the endometrium, and the peritoneum—the smooth, transparent, and highly sensitive membrane that lines the pelvic and abdominal cavity—all originated from the same embryonic cell membrane.

It was then postulated that some of these cells could be transformed into endometrial cells or endometrial like cells through repeated irritation, such as pelvic infections, or by hormonal stimulation. In many cases, the physiological result is identical to having actual endometrial cells run wild and implant themselves: pain, cramps, and possible infertility. Thu mimicking of the disease posed some conclusions that interest scientists. The story that follows reveals why.

*26\43\4*

May 8

Boils are deep infections, usually of hair follicles. They may occur at any age but are most common in adolescence. They can occur at any site except the palms and soles. Friction such as that often felt in the belt or collar areas may predispose to their development. Various diseases such as uncontrolled diabetes may aggravate boils, although very few people with boils have in fact got diabetes. The most common infective organism is the Staphylococcus.

A single boil may require no treatment other than careful washing with an antiseptic soap, causing it to spontaneously discharge. When there are multiple boils, or if one is in a potentially dangerous site, active treatment is necessary. Initially, a penicillinase-resistant semi-synthetic penicillin should be administered—such as Cloxacillin. The pus should be cultured, so that the most appropriate antibiotic can then be selected for further treatment. If boils recur, further investigations are necessary. Cultures should be taken from the infected lesion and from other sites such as the nostrils, normal skin, armpits and genital area. This will identity the reservoir or source of the infective organism. Occasionally cultures taken from other members of the immediate family may be helpful. Appropriate local treatment with an antibiotic cream can then be employed to eradicate the source. Treatment may be assisted by the taking of oral antibiotics and antiseptic baths. Further investigation to exclude possible concurrent diseases such as diabetes and immunological deficiencies may occasionally also be necessary.

Viruses are lengths of nucleic acid which carry enough information for their own replication only. They are therefore completely dependent on the host cells. Unlike bacteria, they do not grow by dividing; they assemble new virus particles by the addition of protein. There are a large number of viruses which affect man and, unfortunately, there are no antibiotics effective in their treatment.

*53\44\4*

May 8

The specific component of carbohydrate we are seeking to increase is fibre. By selecting meals and snacks with a greater fibre content, individuals are likely to increase the intake of starches.

A gradual increase in fibre intake should be recommended. This will minimise possible side effects which include flatulence and possibly diarrhoea. When increasing fibre intake, also check fluid intake. If fluid intake is inadequate, constipation may result due to absorption of water by fibre in the large bowel.

It is also wise to caution clients against an excessive fibre intake. Besides the obvious gaseous effects, large quantities of insoluble fibre—particularly wheat bran—can interfere with the absorption of iron by the body.

Assessing dietary fibre intake. A ‘fibre count’ can be performed to identify sources of fibre and opportunities for increased intake. A greater fibre intake will result from increased consumption of fruits, vegetables, wholegrain cereals, legumes and other unprocessed plant foods. Client education should promote an eating style which includes these foods. As this list is limited to major fibre-containing foods, it can only provide a rough estimate of dietary fibre eting habits.

Reading food labels for carbohydrates. Nutrition information panels indicate carbohydrate content by showing the ‘total carbohydrate’ and the quantity of ‘sugars’ per 100g. The starch content can be calculated by subtracting sugars from the total. This is a comparison between white and wholemeal bread. Both breads contain a relatively large amount of starch—44.4g and 40.7g respectively. Although technically carbohydrate, fibre content is shown separately. As you would expect, wholemeal bread contains more fibre.

In the absence of a nutrition information panel, an ingredient list can give an indication of the fibre content of a food. Names such as wholewheat, bran, wheatbran, wholegrain, wheatgerm, wheatmeal and oatbran appearing near the front of an ingredient list may indicate a generous fibre content.

An ingredient list can also provide an indication of sugar content. Sugar can be identified by numerous other names: sucrose, maltose, lactose, dextrose, fructose, glucose, sorbitol, mannitol, glucose syrup, com syrup, golden syrup, disaccharides, monosaccharides, polysaccharides, modified carbohydrate, raw sugar, brown sugar, molasses, honey and treacle.

Nutritional claims about carbohydrates. Like fat, there are requirements for manufacturers’ claims about fibre in food.

*106\186\4*

May 8

As a result of the tests carried out your doctor will advise you as to the best course for a desired pregnancy.

If all is normal with your partner’s semen analysis it may be suggested that you are failing to ovulate and that a course of fertility drugs such as Clomiphene (Clomid) be taken to induce or increase egg production.

You will be told to start taking Clomid on either day 2 or day 5 (depending on the length of your cycle).

If a pregnancy still has not occurred after several months you may be advised to try a combination of Clomid with ultrasound scans and injections of HCG (human chorionic gonadotrophin).

The Clomid will encourage the production of an egg(s), the ultrasound scan will determine its maturity and the HCG injection will ensure it is released into the fallopian tube within 3 6 hours. You will be told to coincide intercourse during that 36 hours.

If these treatments are not successful you will need to consider your options. At this stage the options may include deciding to have no further treatment or to investigate your suitability for IVF (in vitro fertilisation) or GIFT (gamete intra fallopian transfer). However, before embarking on either of these programmes it should be noted that the success rates for full term pregnancies is 10% and 20% for IVF and GIFT respectively.

*96\83\2*

May 8

A definite diagnosis of endometriosis is one made when a gynaecologist has actually observed endometrial implants or cysts in your pelvic cavity during a laparoscopy (a minor surgical operation using a laparoscope) or, occasionally, a laparotomy (major abdominal surgery).

In general, a laparoscopy is the preferred method of diagnosing endometriosis because it is a simpler and shorter operation and the use of the laparoscope enables better detection of small implants as it magnifies them to several times their actual size.

Classical endometrial implants and cysts can usually be easily recognised and diagnosed by a gynaecologist during a laparoscopy. However, atypical implants and microscopic endometriosis can be missed if the gynaecologist relies only on a visual impression. An increasing number of gynaecologists are using biopsies to diagnose endometriosis in doubtful cases. This involves removing a sample of tissue, known as a biopsy, from any area that the gynaecologist thinks may be the site of an endometrial implant for examination and diagnosis under a microscope.

A definite diagnosis is extremely important as it enables an accurate assessment of the severity and extent of the disease to be made and provides a guide as to the likely effect of the condition on your fertility. This is essential information if you are to think about and make informed decisions regarding the management of your endometriosis.

The Commonwealth Department of Community Services and Health, which administers the Pharmaceutical Benefits Scheme, will not subsidise the cost of some of the drugs used in the treatment of endometriosis unless a definite diagnosis has been made.

*37\83\2*

It stands to reason that being at all overweight is not going to help your sciatica or back problems one bit. As we’ve seen, the spine’s design is such that it all too often has difficulty in coping with even the normal, ordinary demands put upon it through everyday living. If the burden it has to bear becomes even greater because you’re overweight, then it’s obviously more likely that something is going to give sooner or later.

There’s an additional point to take into account: most overweight people carry their extra pounds in the abdomen area, the hips and the thighs. Extra weight in the abdomen is particularly bad news for back sufferers because its presence not only puts extra strain upon the spine while you’re erect – such as standing or walking – but even when you’re sitting. And, of course, bending over or lifting anything creates even greater demands upon the spine when there’s excess baggage hanging out in front of it.

Keeping your weight down to a reasonable level can make a major difference in both preventing and easing back problems and sciatica. What’s more, of course, keeping to a healthy weight will also pay rich dividends in other health benefits. Additionally, many of the exercises that are so important to maintaining a flexible and trouble-free spine will be a great deal easier to do if you’re not carrying too many extra pounds- and a lot more fun, too! It’s a fact that the overweight – the very people who would perhaps gain the greatest benefits from frequent and regular exercising – are often those who exercise the least, part of the reason for this obviously being that exercising is all that much harder and therefore less appealing for them. This lack of exercising often imposes a double penalty upon the back: firstly, it is likely to contribute to the putting on of ever more extra weight; secondly, because the back muscles are not exercised, they’re likely to be in poor condition, lacking strength and flexibility, providing less efficient support for the back and the spine as a whole.

Faced with an obese patient with recurrent sciatica or other back problems for which no other obvious treatment is indicated, doctors will often recommend a weight-loss programme. Good though that advice is, most doctors unfortunately do not have the time to provide specific guidelines about how best to shed the pounds. Following are some of the things your doctor might suggest if he had the time.

*41\124\2*

As you can imagine, with all the symptoms I have just listed, including a grim and bleak view of your present situation and future prospects, a depressed person may easily reach the conclusion – or entertain the possibility – that life is not worth living. This symptom of depression, known to the clinician as suicidal ideation, is a very troublesome one. If you are experiencing any such ideas, please do yourself and everyone who cares about you a great favour and consult a doctor without delay. Depression is a condition where hope is in short supply and one way to get an infusion of hope is to reach out to those who may be able to guide you out of the dark place. Your GP is a logical first port of call in such an attempt to reach out. But if, for any reason, it is difficult for you to talk to your doctor about the problem, tell someone – a family member, friend, or even someone on a crisis hot line. Suicidal ideation is not a symptom that anyone ought to have to suffer alone.

As depression deepens, suicidal ideation may progress to passive suicidal longings, which may be accompanied by lack of self-care or carelessness. A depressed woman may feel a lump in her breast while taking a shower and may say to herself, ‘So what if it’s cancer? It would probably be all for the best anyway’ Another depressed person might cross the road carelessly and, in the back of his mind, be thinking, ‘Well, if I get run over, what loss will that be to anyone?’

Matters become even more serious when suicidal ideas begin to gel into actual plans, and even more so when actions are taken to put these plans into effect. It might seem unnecessary to say that if someone you know or love should mention suicidal ideas or plans to you, these should always be taken seriously. Unfortunately it is still all too common for people to minimize the seriousness of such communications. The idea that if someone tells you he is considering suicide, he is unlikely to act on it, is a very dangerous myth. Such divulgences should always be heard as a communication of despair, which may or may not involve immediate danger but which always warrants serious attention. At the very least it is an expression of severe mental anguish.

If you think that life is not worth living or have any thoughts or plans to end your life, you are very, very likely to be depressed. Please don’t delay in getting professional help for this problem.

*58\75\2*

Automobiles represent an important source of environmental problems. It has been pointed out in the case of Nora Barnes and other patients that some individuals react to even supposedly “harmless” amounts of automotive exhaust fumes (Chaps. 3 and 7). For this reason, the consumer should think ecologically when buying an automobile. There are five basic rules to follow when purchasing a car:

1.    The car should have a valve which turns off the air intake. This is

important, since one may run into unexpected sources of fumes on

the road: a garbage dump, freshly tarred road, airport, driving through

tunnels or unusually heavy traffic.

2.    Choose the car upholstery with forethought. The best kind of upholstery

is leather, although this has become very difficult to find in American cars. The next best choice is rayon, a fabric made from cellulose, itself a wood by-product. Nylon is less objectionable than the newer synthetic fabrics such as vinyl.

3. The car should have push-button windows, to allow the driver to simultaneously raise all the windows when approaching a major source of pollution.

4. All rubber mats should be removed from the floor of the car and the trunk and should be replaced with carpeting, preferably made from natural fibers.

5. The car should be equipped with an activated carbon filter to clean up fumes which have accumulated on the inside. This is particularly important for those who are known to have a moderate-to-severe form of chemical susceptibility. Sources for such filters are given in the Colos book.

In general, one should be most careful when purchasing a car. It should be driven on the highway first, to see if unpleasant health symptoms develop when riding in it. There may be an undetected leak in the exhaust system, and any prepurchase inspection should pay careful attention to this part of the automobile. The car should preferably be tried out on a sunny, warm day, for plastic car upholstery can cause problems when heated. One should never buy a car which is a source of environmental problems or which causes or perpetuates symptoms.

Once a car is purchased, it is necessary and important to keep car fumes out of the living quarters. If there is a choice, avoid a house whose garage is located under or adjacent to the living area. The case of Sister. Francesca, who fell asleep after being exposed to fumes from a still-hot car engine, illustrates the potential for reactions.

Detached garages are best. If the car must be stored in an adjacent garage, it should be allowed to cool completely, away from the house, before it is put away.

In choosing a house site, one should make sure that it is not located too close to any major road or highway, especially one on which busses travel. The direction of the prevailing winds should be taken into account as well. Check to find out if a new highway is planned for the neighborhood. Patients sometimes choose an ideal country spot for building an ecologically sound house, only to wake one morning to the sound of highway-building equipment.

*109\110\2*

As more and more people take up wilderness river rafting as a means of getting back to nature, the number of plant poisoning cases has been on the increase. Ingestion of the water hemlock plant (known as Cicuta douglasii), the Western Journal of Medicine (142:637) reports, has recently been responsible for the deaths of several river rafters in Oregon and Idaho.

This plant closely resembles the wild carrot or parsnip. It has large fleshy roots with a smell so strongly suggestive of carrots and celery that people are tempted to taste them.

Unfortunately, however, the water hemlock is one of our most poisonous wild plants and can bring on convulsions, collapse, and death, all within an hour or two after one has taken a small bite of its root.

About the only method of treating hemlock poisoning available in the wilderness is the induction of vomiting, but, without an emetic such as syrup of ipecac, this can be very difficult. Campers, therefore, should always be prepared for such emergencies by carrying a reliable emetic in their packs.

In emergencies, a useful trick that can save lives from poisoning, according to the Journal, is to make up an emetic by mixing a tablespoonful of liquid dish soap in eight ounces of water.

*187\143\2*

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